Frequently Asked Questions

Can I use naloxone on myself?

• No, naloxone is administered to someone after an overdose has occurred. Because the individual who overdosed is likely unconscious and/or their movement and breathing are restricted, they would need assistance.

Will taking Naloxone prior to opioid exposure prevent an overdose?

• No, naloxone cannot be taken prior to using drugs to prevent an overdose.

Is naloxone addictive?

• No, naloxone is safe to use and is not addictive.

Is naloxone easy to use?

• Yes, naloxone is easy to use and medical training is not required. Check out CDC’s videos on how to use naloxone nasal spray and how to use injectable naloxone.

How many doses of naloxone do I need to give if someone is overdosing?

• Naloxone is a fast-acting drug that can reverse opioid overdose and restore normal breathing within 2-3 minutes.3 Additional doses of naloxone may be needed for larger quantities of opioids or more potent opioids, like fentanyl. If the person who has overdosed remains unresponsive, keep giving additional doses (if available) until they’re alert or until emergency assistance arrives.

Does naloxone have side effects?

• Naloxone can (but does not always) cause withdrawal symptoms or unpleasant physical reactions, in people who are physically dependent on opioids. Withdrawal symptoms may include fever, anxiety, irritability, rapid heart rate, sweating, nausea, vomiting, and tremors.

Is naloxone harmful?

• Naloxone won’t harm someone if they’re overdosing on opioids or other drugs, so it’s always best to use it if you think someone is overdosing.

Can anyone carry naloxone?

• Yes, anyone can purchase and/or carry naloxone to help respond to an overdose. It is not just for people with an opioid or other substance use disorder. Having naloxone available allows bystanders to help save lives by preventing a fatal overdose.

https://www.cdc.gov/stopoverdose/naloxone/faq.html